Decreased Concentration Of Phenacetin In Plasma Of Cigarette Smokers [ http://moodle.iesvalledelsaja.es/user/view.php?id=2190&course=1 ]
To estimate the Ki value, different concentrations of phenacetin (12.5, 25, 50,100, 200 µM) and baicalin (0, 10, 20, 40, 80 µM) were used in pooled HLMs (n = 9). The 9 individual HLMs were selected according to CYP1A2 genotype and the value of Km from the 28 individual HLMs. When the iron of hemoglobin is oxidized to Fe3+, it is unable to carry oxygen.